Puo’ causare ictus e Alzheimer, scoperto il killer dei neuroni – Adnkronos

 

Scoperto il killer dei neuroni, un nemico capace di causane la morte

La stessa catena di eventi molecolari sembra, infatti, responsabile della morte delle cellule cerebrali per ictus, lesioni e persino malattie neurodegenerative come il morbo di Alzheimer. Ora i ricercatori della Johns Hopkins University dicono di aver individuato la proteina che si cela alla fine di questa catena di eventi, quella cioè che dà il colpo fatale ai neuroni, attaccando dall’interno il Dna della cellula. La scoperta, dicono i ricercatori, potenzialmente apre una nuova strada per lo sviluppo di farmaci in grado di prevenire, fermare o indebolire questo processo.

Lo studio sul killer dei neuroni è pubblicato su ‘Science’….continua su : www.adnkronos.com/salute/medicina/2016/10/06/puo-causare-ictus-alzheimer-scoperto-killer-dei-neuroni_gNdu8mkZQXpoSb7NJ7Kd4L.html

Neuron Killers | Science News

Misfolded, clumping proteins evade conviction, but they remain prime suspects in neurodegenerative diseases

As open-and-shut cases go, Alzheimer’s disease should top the list. The victim is clear. Suspects are in custody. Wherever neurons die due to Alzheimer’s disease, a protein known as amyloid-beta is always found at the scene of the crime, hanging around in large, tough gangs called plaques. Parkinson’s and Huntington’s diseases; amyotrophic lateral sclerosis (which goes by its initials ALS or the alias Lou Gehrig’s disease); and prion diseases, such as scrapie in sheep, mad cow disease in cattle and Creutzfeldt-Jakob disease in humans, all have similar stories.

Scientific investigators have pieced together this much: A seemingly mild-mannered brain protein falls in with a bad crowd, the corrupted protein and its cronies gang up and mob violence results in the death of a brain cell. It’s a scene repeated over and over again in different neighborhoods of the brain, by different proteins, but all with the same result — the death of neurons and rise of disease…Source: www.sciencenews.org/article/neuron-killers